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These risks include heart attack, stroke, and liver failure

However, the compounded version of semaglutide, as discussed above, is not, so it does not have an indication for weight loss

Patients with known liver disease, history of gastrointestinal bleeding, or those taking anticoagulant or antiplatelet medications face higher risk for significant bleeding complications and should have a lower threshold for seeking emergency care

Note: These symptoms are rare, but they can indicate an issue with the bile ducts or pancreas that requires clinical intervention

GLP-1 RAs continue to be a cornerstone of antidiabetic therapy but should not be misconstrued as a panacea