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Research overwhelmingly describes the safety of GHK-Cu positively, such as when the authors of a 2018 review called it a safe, inexpensive, extensively studied compound.14 However, even though copper peptides have demonstrated an impressive safety track record in studies, there are (as with most skin care actives) a few safety risks to consider

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As a result, the extent to which ISOS recommendations are reflected in binding regulations remains uncertain

Avoid heavy or fatty meals 4 hours before bed