5 The bioactive forms, GLP-1(737) and most abundantly, GLP-1(736)NH 2 , are inactivated by dipeptidyl peptidase-4 (DPP-4)
According to reported trial data, adults taking the 12 mg dose lost an average of 70.3 pounds, equal to about 28.3% of body weight, over 80 weeks
Rotating between injection sites on the abdomen, thigh, and upper arm helps reduce the risk of local reactions
However, medications used for the domiciliary management of early symptoms, notwithstanding their importance, have not been and are not presently regarded with the same attention and seriousness
What prescription regimen should be given to a type 2 diabetes patient currently on metformin and glipizide, including metformin dosing, initiation and titration of semaglutide (GLP1 receptor agonist), and guidance on discontinuing glipizide or using empagliflozin as an alternative?