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Women who become pregnant or are planning conception should discontinue tirzepatide and discuss alternative diabetes therapies with pregnancy safety data

The stock sold off sharply again in the following weeks on what felt like any marginally negative datapoint, ultimately revisiting the $35 area in March, a level below where Novo traded before injectable Wegovy was even approved for obesity

Manufacturing at scale can be somewhat challenging, with lots of possible ways to go wrong, says Mansoor Amiji from Northeastern University in Boston, US, but it is still more akin to making a small molecule than a biological drug

By mimicking GLP-1, semaglutide helps control hunger and reduce food intake