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Among patients with obesity, semaglutide 7.2 mg reduced body weight by more than 18% for those without diabetes and by more than 13% for those with diabetes, according to the results of the STEP UP and STEP UP T2D trials
For patients with significant cardiovascular concerns, cardiology consultation before initiating tirzepatide may be appropriate to ensure comprehensive risk assessment and optimize cardiac management
If its urgent progressive condylar resorption, severe sleep apnea, an ankylosed joint, something actively getting worse the conversation is different and has to be individualized
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