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Chimeric class I PtGRXs containing the class III GRX-specific SCCMC motif instead of the YCGYC (PtGRXC1) or YCPYC (PtGRXC4) motifs, respectively, showed moderately to severely reduced oxidoreductase activity depending on the construct, allowing the conclusion that the peculiar active sites of class III GRXs are principally permissive for oxidoreductase activity

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Antioxidant Role: Glutathione, as an antioxidant, may actually help protect melanocytes from oxidative stress, which is one of the factors contributing to premature hair greying

, 2013, Advance Article DOI: 10.1039/C3NJ00978E Interested in reading further