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Understanding how these two substances work independently is essential before considering their combined use
Prolonged treatment of neuroblastoma cell lines with standard chemotherapy agents, etoposide or doxorubicin showed increased levels and synthesis of GSH, increased expression of -glutamyl-cysteinyl ligase, and decreased depletion of GSH [58, 65]
The calculation procedure can be found in Additional file 1: Fig S2
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