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When IgG4-RD affects the head and neck region, it can lead to a range of symptoms, including unexplained headaches that dont respond to standard treatments
364 The affected astrocytes demonstrate profound loss of function, in particular impaired K + buffering, 365,366 compromised H + transport, 367 and substantial decrease in glutamate uptake
Possible redness, swelling, or small knot formation can occur and typically resolves within several days
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