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Nevertheless, the most commonly found side effects of long-term and/or overuse of PPIs are described further

I assess the appropriateness of the medication carefully and monitor closely when [these patients] are on a GLP-1 agonist. The caution is warranted, according to John Batsis, MD, an associate professor of medicine in the Division of Geriatric Medicine at the University of North Carolina at Chapel Hill School of Medicine, particularly because of the lack of clinical data on the specific impact of GLP-1 medications on older adults

Agric Sci 8(9):10481064

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It may in fact have the opposite effect since Glutathione may help to increase muscle mass.