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A phenomenon called metabolic adaptation occurs after weight loss, in which your metabolic rate (the number of calories you burn at rest) decreases to a greater extent than expected based on your new weight
Recurring themes that surface repeatedly include: Local vs systemic is the central talking point
For CagriSema, there was a 14.4% reduction in lean soft-tissue mass
Murata M, Mihara M, Hasegawa K, Jeon B, Tsai C-H, Nishikawa N, Oeda T, Yokoyama M, Robieson WZ, Ryman D, Eaton S, Chatamra K, Benesh J
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