Because NNMT intersects NAD salvage, pairing with NMN/NR is a common experimental strategy to test additive or synergistic effects on cellular NAD and metabolic endpoints
Strongest human evidence The METAOD006 (OPTIONS) Phase 2b trial randomized 502 adults with obesity (BMI 30-45 kg/m^2) to oral AOD-9604 (0.25, 0.5, or 1 mg/day) or placebo for 24 weeks alongside a supervised diet and exercise program
Unlock the Science Ingredient How it Works Accelerates healing of muscles, tendons, ligaments, and joints by upregulating growth factors Repairs the gut lining and reduces GI inflammation, supporting digestive health and leaky gut Stimulates angiogenesis and nerve regeneration to restore function at injury sites Reduces systemic inflammation to improve mobility, comfort, and overall recovery speed Protects and repairs the gastrointestinal tract, including ulcers and inflammatory conditions Drug Facts Peptide therapies are not FDA-approved for anti-aging but are commonly prescribed off-label in regenerative and hormone optimization clinics
Are high doses more likely to cause acne
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