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Dimitriadis et al., 1993
J Gerontol Ser A
Initially used for hydration and medication delivery in the early 20th century, IV therapy expanded its role in emergency medicine and surgery during the 1950s and 1960s
Regarding treatment strategies, it is suggested that the marked decrease in GPx1 expression may be the major mechanism of tumor sensitization to anthracyclines [93] and that GPx1 can partially inhibit doxorubicin-induced cell death-related signaling in breast cancer by interfering with the activation of the sphingomyelin-ceramide pathway [85]
Medication use, infection risk, imaging, and physical exam findings matter more than labs alone
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