WB2086, a human PAF receptor antagonist, inhibits PAF-induced platelet aggregation in animal models (152)
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| Concentration | BAC Water | Doses at 1.0mg | Doses at 2.4mg | |---------------|-----------|----------------|----------------| | 5mg/mL | 2.0mL | 10 doses | ~4 doses | | 2.5mg/mL | 4.0mL | 10 doses | ~4 doses | **Best practice:** 2.0mL BAC water gives a clean 5mg/mL concentration
Reduced Barrier to Entry: For certain types of research, particularly those involving less invasive methods or broader participant groups, an oral formulation could significantly lower the barrier to entry
doi: 10.1136/annrheumdis-2014-205809 307 CribbsAPTerlecki-ZaniewiczSPhilpottMBaardmanJAhernDLindowMet al