Several promising biomarkers have been identified from APAP-overdose research, such as elevated levels of acetylation of the DAMP molecule HMGB1, which correlates with poor prognosis and outcome [267]
Long-term toxicity Continuous injection of AOD 9604 (10 mg/kg) for 8 weeks did not cause abnormal liver and kidney functions or fluctuations in blood glucose
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They are not approved for human or veterinary use, and are not intended to diagnose, treat, cure, or prevent any disease
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