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doi:10.1016/j.beem.2018.06.007 Wilding JPH, Batterham RL, Calanna S, et al
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Analysis of blood parameters confirmed improvements in key markers of glucose and lipid metabolism, such as blood lipid levels, cholesterol, liver damage markers, and HOMA-IR
Tirzepatide should not be used in patients with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 (MEN 2), as these conditions significantly increase thyroid cancer risk
Possible downsides include nausea, constipation, fatigue, and appetite rebound if stopped too quickly
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