Long-acting agonists include liraglutide, exenatide(Bydureon), albiglutide, dulaglutide, semaglutide, PEG-loxenatide and tirzepatide, which can maintain an appropriate agonist level in plasma throughout the 24 hours of the day
Other Side Effects Observed: Increased heart rate (peaked at 24 weeks, then decreased) Fatigue (especially early on) Hair thinning (from rapid weight loss, usually temporary) Injection site reactions What About Serious Side Effects
In addition, these medications arent quick fixes
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Physicians should also adopt a sensitive, patient-centered approach: explain that these are tools to improve health (not a quick fix), set realistic expectations, and address weight stigma