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doi: 10.1038/nrendo.2012.49 133 VintsWAJLevinOFujiyamaHVerbuntJMasiulisN

Interaction of LPS with TLR4 on the surface of adipocytes and macrophages triggers signaling cascades via the MyD88 or TRIF adaptors, leading to NF-B activation and induction of pro-inflammatory genes encoding IL-1, IL-6, and TNF- (Cani et al., 2007

- Arterioscler Thromb Vasc Biol 29:184350 Laviola L, Leonardini A, Melchiorre M, Orlando MR, Peschechera A, Bortone A, Paparella D, Natalicchio A, Perrini S, Giorgino F (2012) Glucagon-like peptide-1 counteracts oxidative stress-dependent apoptosis of human cardiac progenitor cells by inhibiting the activation of the c-Jun N-terminal protein kinase signaling pathway

Tgliche Zufuhrempfehlung Obwohl die Erhhung des innerzellulren Glutathionspiegels bei einem Mangel und bei vielen Krankheiten angezeigt ist, ist eine orale Einnahme meist nicht sinnvoll