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Mann JF, Orsted DD, Brown-Frandsen K, Marso SP, Poulter NR, Rasmussen S, et al

Medical organizations agree that obesity is influenced by many factors, including diet, activity level, environment, and genetics

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Gensous N, Sala C, Pirazzini C, et al

Similar to the transcriptomic changes observed in the hypothalamus, we found that the conjugate prompted transcriptional patterns enriched for functional terms associated with synaptic transmission, including postsynaptic specialization and neuron-to-neuron synapse in the brainstem (Extended Data Fig