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Name: online weight loss consultations semaglutide treatment vs Tirzepatide for Ozempic Weight Loss Injections Near
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Early clinical trial data, most notably from the Phase 2 trial published in the New England Journal of Medicine (Jastreboff et al., 2023), demonstrated that retatrutide produced substantial reductions in body weight up to approximately 24% over 48 weeks at the highest doses studied

For context, the fat-mass reductions reported in Billon 2024 roughly 25-30% in diet-induced obese mice over 28 days without exercise are large for a preclinical metabolic agent and explain why the "exercise mimetic" label stuck