long term effects semaglutide complications from What are the long-term side of after 3+ years Safety & Side Effects Ozempic and Weight Loss Drugs:

The Fix: Start with smaller meals and eat slowly Avoid fried, spicy, or overly rich foods Stay hydrated and include fibre-rich foods If symptoms persist, speak with your doctoryour dose may need adjusting Mistake 3: Skipping Behaviour Change Some people get fixated on the number on the scale and forget that lasting weight loss requires habit change

These symptoms typically diminish as the body adjusts

Geyer MC, Sullivan T, Tai A et al (2019) Exenatide corrects postprandial hyperglycaemia in young people with cystic fibrosis and impaired glucose tolerance: A randomized crossover trial

The US rate of obesity is more than 40% and 26% in the UK, France at 10% and Germany at 23%

STEP 1 figure is treatment policy estimand (ITT)