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In three studies, Hlscher and colleagues reported that GLP-1 mimetics have prophylactic effects and reduce Alzheimer-like disease progression in the APP/PS1 mouse model
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Thus, the downstream signaling activated by altered microbial metabolites and microbiota composition promotes the pathogenesis of metabolic diseases such as obesity and diabetes (94, 95) (Figure 4)
doi:10.1016/j.sleh.2021.05.004
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