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First, targeting one pathway can affect the function of other signaling pathways (i.e., a pleotropic phenomenon)
Based on a sensitivity analysis with a maximum 5-year follow-up time, exposure misclassification introduced by long follow-up times might explain only partly this null association
The class includes several medications, but semaglutide, sold under brand names including Ozempic for diabetes and Wegovy for weight management, has become by far the most widely used
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