Johnson & Johnson UroGen Pharma Ltd
HUMs VP of Content, Brooke Danielson, breaks it all down
We also compared these two groups with a cohort of healthy controls (HCs, unexposed to SARS-CoV-2), and with patients suffering from a severe form of acute COVID-19 (A) who were admitted to the Intensive Care Unit (ICU)
In contrast, subacute etiologies (idiosyncratic DILI, indeterminate causes) involve ongoing, smoldering hepatocyte destruction over weeks, which continuously undermines the regenerative response
In honor of patient#1, the investigators named this novel ACOX1-mediated disease Mitchell Syndrome (distinct from Mitchell's disease, Erythromelalgia)