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"GLP-1 medications naturally reduce appetite, and for some people they also reduce thirst, so it's easier to fall behind on fluids during hot weather." The Centers for Disease Control and Prevention recommends drinking two to four glasses of fluids each hour for prevention of heat-related illness, a goal that might be harder to achieve for patients on a GLP-1

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Wadden TA

This study also shows an increase in reduced glutathione activity in the magnesium and insulin treated rats which also suggest a potentiating effect of magnesium and insulin on reduced glutathione production in these treatment groups

Apply OTC hydrocortisone 1% cream directly to the site