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Although not definitively proven, this risk has been a significant concern, particularly with long-term use

However, it is known to have no moderate or serious interactions with other drugs

[1] Dambrova, M., & Liepinsh, E

Recently, it was shown that cysteine uptake via excitatory amino acid carrier 1 suppresses ischemia-induced neuronal death through promotion of hippocampal GSH synthesis in ischemic animal models (162)

First-line management includes drinking 1.52 litres of fluids daily, using paracetamol (maximum 4 g daily) or ibuprofen (maximum 1.2 g daily for over-the-counter use) as appropriate, and resting in a quiet environment