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These effects typically diminish as your body adjusts, especially with slow dose escalation

And I encourage individuals listening to this podcast, if you're on a GLP and you don't feel like you're doing well, that is something your doctor wants to know about

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However, a retrospective cohort study published in Diabetes Care did find that use of GLP-1 medications for 1-3 years was associated with a slightly increased risk of all thyroid cancer (adjusted hazard ratio 1.58) and medullary thyroid cancer specifically (adjusted hazard ratio 1.78)