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A preclinical pilot study in human patients with chronic pain episodes found, that DSIP significantly reduced pain perception, also improved mood by reduction of depressive states, and that it may potentially be of interest for research into physiological addiction on pain medications, as it was observed to reduce withdrawal symptoms that occurs after discontinuation of long-term analgesic treatment

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7 If these treatments do not improve glycemia or if patients stop producing insulin, doctors may prescribe insulin in combination with other drugs to be injected directly by patients