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A satisfactory explanation of this situation will require further studies

Clinically, however, the evidence is mixed : Vitamin B12 has a well-established role in energy metabolism, especially in deficient individuals

In liver injury, CHAC1s promotion of GSHdegradation accelerates oxidative stress and liver cell death, while in atherosclerosis, it contributes to plaque instability by promoting apoptosis in lesional macrophages and smooth muscle cells (Xu et al., 2023