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Alcohol is packed with carbs but has zero nutritional value, so your body torches its Thiamine reserves to process it
Mitochondria contain multiple copies of their own genome, mitochondrial DNA (mtDNA), which encodes for 13 polypeptides of the OXPHOS and respiratory chain, as well as two ribosomal RNAs and 22 transfer RNAs necessary for translation of polypeptides inside mitochondria
Mechanistic explanations include copper-dependent enzyme cofactor support and signaling-pathway activation
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Thus, elevated oxidative stress does not merely accelerate the progression of atherosclerosis, but can also increase the risk of plaque rupture, which may directly lead to a thrombotic event
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