glp 1 tri LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept Development of a potent Xenopus

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Studies have shown that GLP-1 treatment significantly increases the expression levels of BTG2, Pdx1, and the insulin gene in pancreatic cells, indicating that GLP-1 positively regulates insulin gene expression through BTG2, thereby promoting insulin synthesis (Hwang et al., 2013)

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68 , 404417 (2012) Emsley, P., Lohkamp, B., Scott, W