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Measurable concentrations exist in human blood plasma, and those concentrations respond to physiological states

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Research indicates that copper is a critical component of antioxidant enzymes like superoxide dismutase (SOD), which protect cells from oxidative damage

Fluid retention and edema: During treatment with glucocorticoids and diclofenac, edema and fluid retention have been observed so the formula must be used with caution in patients with a history of decompensation, hypertension or other factors predisposing to fluid retention