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Owing to its flexibility, this strategy can be implemented in both Boc- and Fmoc-based solid-phase peptide synthesis (SPPS), as well as in solution-phase peptide synthesis

Thyroid hormones regulate numerous metabolic processes: Basal metabolic rate and energy expenditure Protein synthesis and cellular metabolism Cardiovascular function including heart rate and contractility Growth and development in multiple organ systems Levothyroxine is typically taken once daily on an empty stomach, ideally 30-60 minutes before breakfast

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