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Both immunosuppressants have steep concentration-toxicity relationships

GSH dysregulation might cause global immune cell autophagy decline with increased generation of proinflammatory cytokines in aging, further provoked by mitochondrial ROS signaling (293)

Next, the samples were concentrated in SpeedVac (Savant) under vacuum for 40 min, and the concentrated samples were re-constituted to the original volume by 10 l of Millipore water

Heise T, De Vries JH, Coskun T, Urva S, Li J, Pratt EJ, Thomas MK, Mather KJ, Dunn JP, Haupt A, et al