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This could be interpreted as alarming and signaling that we should lengthen NPO times, particularly in diabetic patients who may have undiagnosed gastroparesis, or it could potentially be seen as reassuring, indicating that maybe a low volume of gastric contents isnt as big of a risk factor for aspiration as once thought.1 The authors of this paper recommend that patients be fasted from solid food for 24 hours

All weight loss leads to both fat and muscle loss, which can be a concern, especially in people who are already frail

For very lean individuals with minimal subcutaneous fat, a 45-degree angle may be better to avoid injecting into muscle

Hims can still produce these drugs if there is another shortage or if there is a clinical necessity for personalization of the drug

Casares, N