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By contrast, several mutations that decrease the tone of the GH/IGF-1 axis are associated with extended longevity in mice

Amino acid metabolism has extremely extensive effects in cancer cells, including, but not limited to, (1) establishing amino acid pools as building blocks, especially the production of non-essential amino acids for protein biosynthesis, conversion to glucose, lipids, and precursors of nitrogen-containing metabolites, such as purines and pyrimidines for nucleic acid synthesis

In case you missed it, here is a link to part 1 of this series