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doi: 10.3389/fphar.2018.01162 268 TanH.-Y.WangN.LiS.HongM.WangX.FengY

Where evidence is sparse, it appears that prescribing cultures can develop, likely reflecting local opinion leaders and shared training networks, which may explain otherwise unjustified practice variation (examples including the Australian preference for hydromorphone and the shared antipodean favour towards magnesium and Crampeze over quinine)