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Overall, injecting CD5/ LNP-FAPCAR 2.2 significantly reduced the number of FAP-positive cells and rescued pulmonary fibrosis while treatment with PFD provided limited relief from fibrosis, which was possibly due to the short duration of the medication

(Peptide Sciences) While senescence is protective in acute contexts (e.g., preventing malignant transformation, wound repair), the accumulation of senescent cells over time is detrimental: They occupy tissue space and resources, impairing progenitor cell function

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