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However, high dose vitamin E supplements those which provide more than 300 mg per day can interact with the blood thinners aspirin and warfarin ( They can also interfere with tamoxifen, a drug used to treat breast cancer, and cyclosporine, an immunosuppressant used by people who have received an organ transplant ( If you have any concerns about potential interactions between vitamin E supplements and your medications, you should consult your healthcare provider

doi: 10.3390/biology10060495 111

Severe depletion in liver glutathione during physical exercise

Some protocols call for 24 hours maximum at room temperature