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It is the only clinically approved GHR antagonist and has been approved by the FDA for the treatment of acromegaly [reviewed in ref
No claims are made regarding safety, efficacy, or therapeutic application
These studies all indicate that diet can influence the make-up of cell membranes and thus, we hypothesise that it may have a potential direct regulatory impact on incretin receptor function in target cells
cDNA constructs of the human GCGR was donated by Professor Patrick Sexton (Monash University, Australia) while cDNA constructs of human GPR119 were purchased from cDNA.org
doi:10.1111/dom.14280
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