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Patients should never adjust doses without medical guidance, and treatment should be reviewed if side effects significantly impair quality of life

Hormonal birth control, adventurous eating, a few too many drinks, new medicationthe list goes on

147 Another antitumoral effect of KD is upregulating the expression of the circadian clock gene Per (Period) by activating AMPK and upregulating SIRT1 (Sirtuin1), resulting in enhanced apoptosis and growth delay in tumor cells

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Increasing NAD + levels could also stabilize telomeres and help recovery of elderly PASC patients 528