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Pancreatitis: There have been reports of pancreatitis (inflammation of the pancreas) associated with the use of Ozempic
Specifically, tirzepatide increases adiponectin, a protein hormone that regulates the breakdown of fatty acids
The flagship trial STEP-1 (published in NEJM , 2021) found a mean weight reduction of ~14.9% of body weight with semaglutide 2.4 mg vs ~2.4% with placebo over 68 weeks ( [12] )
She, J., Sheng, R., & Qin, H
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