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The efficacy and safety of the new GLP-1 medicines continues to garner interest and will be discussed #ADA2024 Here is an updated safety-focused summary of the field and where it might be headed @DiabetesCareADA #T2D #obesity pic.twitter.com/rtEQYtHQG0 Daniel J Drucker (@DanielJDrucker) June 6, 2024 Investigational GLP-1 medicines in the clinic Late-stage investigational GLP-1 medicines for type 2 diabetes and obesity include new molecules like retatrutide and orforglipron, showing potential differentiation from semaglutide and tirzepatide through better tolerability, greater weight loss, Hb A 1c reduction, and targeted outcomes
Agents targeting modulation of specific signalling pathways Larsucosterol: Larsucosterol is an endogenous sulfated oxysterol that inhibits DNA methyltransferase
One standard drink is generally considered low-risk for most people on retatrutide, but be prepared for that drink to affect you more than it did before starting the medication
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