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A randomized controlled trial published in Nature Medicine in 2019 examined pasteurized Akkermansia muciniphila supplementation in 32 overweight and obese insulin-resistant volunteers

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Updated December 17, 2020

Lifestyle and Behavioral Interventions Medical nutrition therapy (MNT): Low-carbohydrate, Mediterranean, DASH, or plate-method eating patterns

Mild, early side effects of excessive selenium intake may include: Nausea, digestive problems, and diarrhoea Metallic or garlic-like bad breath Fatigue and irritability Headache More severe or chronic overdose (selenosis) can cause: Hair loss and brittle nails Skin rashes or nail discolouration Neurological symptoms such as dizziness or tremors In extreme cases, kidney problems, heart problems, and serious nervous system issues Memory loss and confusion have also been described in some toxicity scenarios, although these are not typical early symptoms