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Similarly, many effects of oxidative stress on the enzymes of one carbon metabolism and the transsulfuration pathways are known but detailed kinetics are not available
Nitric oxide, observed during the inflammatory phase of wound healing, has been shown to compromise collagen accumulation, which is a crucial process in skin health
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We therefore hypothesized that SP exerted its biological effects through the secretion of exosomes
First, 20 mg of chitosan (medium molecular weight, 75% deacetylated, Sigma-Aldrich, USA) was dissolved in 10 mL of 1% (v/v) acetic acid under magnetic stirring (500 rpm, 25 C, 2 h) to yield a 0.2% (w/v) solution, and the pH was adjusted to 4.8 with 1 M NaOH
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