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Addition of the ISR agonist Sephin1 to cultured human OLmaintained under control conditions or exposed to ongoing metabolic stressreduced process outgrowth 42 , suggesting that the ISR regulates the protein synthesis machinery required for OL process outgrowth and maintenance
Tesofensine is generally considered more potent for direct appetite suppression studies due to its neurological mechanism of action
Structurally identical to native exendin-4, exenatide is a chemically synthesized peptide with clinical applications in the management of type 2 diabetes
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