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In another study, examining 112 small intestine NETs (siNETs), 19 pancreatic NETs (pNETs) and 42 NETs derived from other locations, it was demonstrated that 65%, 76%, 90%, 86% and 93% of all cases were recognized by the expression of SSTR1, SSTR2, SSTR3, SSTR4 and SSTR5, respectively [7]

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Small and large-sized tags, including poly-Histidine (19 a.a.), Myc epitope (11 a.a.), maltose binding protein (396 a.a.), Glutathione S-transferase (GST) (211 a.a.), small ubiquitin-like modifier (SUMO) (100 a.a.), galactose binding protein (GBP) (509 a.a.), etc., have all been reported to increase protein expression and solubility [11]