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The effect is especially large in more socially anxious individuals (Pause et al., Reference Pause, Adolph, Prehn-Kristensen and Ferstl2009), in whom there is also evidence for early processing bias towards anxious odour and increased allocation of neuronal resources (Pause et al., Reference Pause, Lbke, Laudien and Ferstl2010)
To further validate the RNF4-independent activity of CCW28-3, we performed an RNF4 KD in HEK293T cells expressing an endogenously HiBiT tagged BRD4 and treated cells with CCW28-3 or CCW16 alone for 4 h, 6 h and 24 h ( Figure 4C, D )
The zeta potential of -31.87 mV confirms strong electrostatic repulsion between particles, preventing aggregation and maintaining uniform dispersion throughout the shelf life
It supports myelin production, which protects nerve fibers, and helps reduce homocysteine levels that are linked to cognitive decline
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