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This pathway is initiated by glucose-6-phosphate dehydrogenase (G6PD), the rate-limiting enzyme essential for maintaining redox balance in the cell ( 4 ) in its active form, and fuels the glutathione-based antioxidant defense system
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Experimental research has explored its interactions with cytokine activity, inflammatory mediators, gastrointestinal tissues, and cellular communication networks associated with immune responses
Therefore, we recommend that companies begin work on these requirements at the beginning of the relevant year or as soon as possible
