Commonly reported side effects include: Nausea, vomiting, or stomach cramps Diarrhoea or loose stools A distinctive 'fishy' body odour, caused by the production of trimethylamine a metabolic by-product of carnitine breakdown in the gut These gastrointestinal effects are more likely at higher doses, particularly above 3,000 mg per day, and are consistent with adverse effects described in the levocarnitine SmPC
ChuZLJonesRMHeHCarrollCGutierrezVLucmanAet al
In a sensitivity analysis, we constructed cohorts in which each participant could only contribute with one treatment episode
They also implemented an automated coding system that alerted them to changes
To adapt to this rapid change in medicine, Temple is adopting a multidisciplinary approach to the disease, building on what is done in cancer care, Stein said