Table 1 Comparison of clinical parameters at baseline (Timepoint 1) with treatment phase (Timepoint 2) and off treatment phase (Timepoint 3)
Foundayo (Orforglipron) A newer option, Foundayo, approved in 2026, brings flexibility by allowing intake at any time without dietary or hydration restrictions
The access factor Perhaps the strongest argument for GLP-1 supplements is access
The changes are significant enough that other people start commenting
According to Jenna Queller, MD, a board-certified dermatologist and founder of DermWorks in Boca Raton, Florida, Melanotan II is a synthetic peptide designed to mimic alpha-melanocyte-stimulating hormone (also known as -MSH), which she describes as a naturally occurring hormone that stimulates melanocytes, the pigment-producing cells in the skin. By activating these receptors, the peptide can increase melanin production and thus make skin look more tan